Influence of low level maternal Pb exposure and prenatal stress on offspring stress challenge responsivity
نویسندگان
چکیده
منابع مشابه
Prenatal maternal stress exposure and immune function in the offspring.
The intra-uterine environment provides the first regulatory connection for the developing fetus and shapes its physiological responses in preparation for postnatal life. Psychological stress acts as a programming determinant by setting functional parameters to abnormal levels, thus inducing postnatal maladaptation. The effects of prenatal maternal stress (PNMS) on the developing immune system h...
متن کاملThe Effect of Prenatal Exposure to Restraint Stress on Hippocampal Granule Neurons of Adult Rat Offspring
Objective(s) It is well known that prenatal stresses (PS) induce a variety of neurobiological and behavioral alterations, some of them involving the hippocampal formation. This study aimed to determine whether restraint stress influences the neuronal volume and number of granule cells in the hippocampus of adult rat offspring. Materials and Methods Ten Wistar pregnant rats were randomly divi...
متن کاملPrenatal maternal stress programs infant stress regulation.
OBJECTIVE Prenatal exposure to inappropriate levels of glucocorticoids (GCs) and maternal stress are putative mechanisms for the fetal programming of later health outcomes. The current investigation examined the influence of prenatal maternal cortisol and maternal psychosocial stress on infant physiological and behavioral responses to stress. METHODS The study sample comprised 116 women and t...
متن کاملthe effect of prenatal exposure to restraint stress on hippocampal granule neurons of adult rat offspring
objective(s) it is well known that prenatal stresses (ps) induce a variety of neurobiological and behavioral alterations, some of them involving the hippocampal formation. this study aimed to determine whether restraint stress influences the neuronal volume and number of granule cells in the hippocampus of adult rat offspring. materials and methods ten wistar pregnant rats were randomly divided...
متن کاملThe influence of maternal prenatal and early childhood nutrition and maternal prenatal stress on offspring immune system development and neurodevelopmental disorders
The developing immune system and central nervous system in the fetus and child are extremely sensitive to both exogenous and endogenous signals. Early immune system programming, leading to changes that can persist over the life course, has been suggested, and other evidence suggests that immune dysregulation in the early developing brain may play a role in neurodevelopmental disorders such as a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: NeuroToxicology
سال: 2008
ISSN: 0161-813X
DOI: 10.1016/j.neuro.2008.09.010